Hedgehog directly controls initiation and propagation of retinal differentiation in the Drosophila eye.

@article{Domnguez1997HedgehogDC,
  title={Hedgehog directly controls initiation and propagation of retinal differentiation in the Drosophila eye.},
  author={M Dom{\'i}nguez and Ernst Hafen},
  journal={Genes & development},
  year={1997},
  volume={11 23},
  pages={3254-64}
}
Patterning of the compound eye begins at the posterior edge of the eye imaginal disc and progresses anteriorly toward the disc margin. The advancing front of ommatidial differentiation is marked by the morphogenetic furrow (MF). Here we show by clonal analysis that Hedgehog (Hh), secreted from two distinct populations of cells has two distinct functions: It was well documented that Hh expression in the differentiating photoreceptor cells drives the morphogenetic furrow. Now we show that, in… CONTINUE READING