Hedgehog acts directly on the zebrafish dermomyotome to promote myogenic differentiation.

@article{Feng2006HedgehogAD,
  title={Hedgehog acts directly on the zebrafish dermomyotome to promote myogenic differentiation.},
  author={Xuesong Feng and E. Adiarte and S. Devoto},
  journal={Developmental biology},
  year={2006},
  volume={300 2},
  pages={
          736-46
        }
}
  • Xuesong Feng, E. Adiarte, S. Devoto
  • Published 2006
  • Biology, Medicine
  • Developmental biology
  • Vertebrate myogenesis is regulated by signaling proteins secreted from surrounding tissues. One of the most important, Sonic hedgehog, has been proposed to regulate myogenic precursor cell survival, proliferation, and differentiation in a variety of vertebrates. In zebrafish, Hedgehog signaling is both necessary and sufficient for the development of embryonic slow muscle fibers-the earliest differentiating muscle fibers. Here we investigated the function of Hedgehog signaling in another… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Building muscle: molecular regulation of myogenesis.
    • 600
    • Open Access
    Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation.
    • 40
    • Open Access
    Dynamic somite cell rearrangements lead to distinct waves of myotome growth
    • 110
    • Open Access
    Pbx homeodomain proteins direct Myod activity to promote fast-muscle differentiation
    • 118
    • Highly Influenced
    • Open Access
    BMP regulation of myogenesis in zebrafish
    • 38
    • Open Access
    Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential
    • 59
    • Open Access
    Hedgehog Signaling Regulates MyoD Expression and Activity*
    • 29
    • Open Access

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 90 REFERENCES
    Hedgehog signaling in animal development: paradigms and principles.
    • 2,675
    • Open Access
    Sonic hedgehog controls epaxial muscle determination through Myf5 activation.
    • 271
    • Highly Influential
    • Open Access
    A Pax3/Pax7-dependent population of skeletal muscle progenitor cells
    • 913
    • Open Access
    The formation of skeletal muscle: from somite to limb
    • 740
    • Open Access
    Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog.
    • 342
    • Highly Influential
    • Open Access