Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder.


Epithelial integrity in metazoan organs is maintained through the regulated proliferation and differentiation of organ-specific stem and progenitor cells. Although the epithelia of organs such as the intestine regenerate constantly and thus remain continuously proliferative, other organs, such as the mammalian urinary bladder, shift from near-quiescence to… (More)
DOI: 10.1038/nature09851


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