Heck's disease: diagnosis and susceptibility.

  title={Heck's disease: diagnosis and susceptibility.},
  author={Lindsey K Bennett and Molly A Hinshaw},
  journal={Pediatric dermatology},
  volume={26 1},
Focal epithelial hyperplasia, or Heck's disease, is an uncommon proliferation of oral mucosa that presents primarily in Native Central and South American populations. It presents as asymptomatic papules or nodules on the oral mucosa, gingiva, tongue, and lips. In the majority of cases, human papilloma virus 13 or 32 is detected. Factors that determine disease susceptibility are unclear, but genetics, and having the human lymphocytic antigen-DR4 (DRB1*0404) allele in particular, are thought to… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 12 references

Mosqueda-Taylor A et al.Association ofHLADR4 (DRB1*0404)with human papillomavirus infection in patients with focal epithelial hyperplasia

C Garcı́a-Corona, E Vega-Memije
Arch Dermatol 2004;140:1227–1231 • 2004
View 5 Excerpts
Highly Influenced

Cutaneous signs of child abuse.

Journal of the American Academy of Dermatology • 2007

Molecular and serological evidence of the epidemiological association of HPV 13 with focal epithelial hyperplasia: a case-control study.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology • 2006
View 2 Excerpts

Association ofHLADR 4 ( DRB 1 * 0404 ) with human papillomavirus infection in patients with focal epithelial hyperplasia

C Garcı́a-Corona, E Vega-Memije, A Mosqueda-Taylor
Arch Dermatol • 2004

Imiquimod for the topical treatment of focal epithelial hyperplasia (Heck disease) in a child

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG • 2004
View 1 Excerpt

Humanpapillomavirus andcervical cancer

A Swerdlin, C Berkowitz, N Craft
Clin Microbiol Rev • 2003

Genetic susceptibility to HPV infection and cervical cancer.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas • 1999
View 1 Excerpt

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