Heavy metal-resistant bacteria as extremophiles: molecular physiology and biotechnological use of Ralstonia sp. CH34

@article{Nies2000HeavyMB,
  title={Heavy metal-resistant bacteria as extremophiles: molecular physiology and biotechnological use of Ralstonia sp. CH34},
  author={D. Nies},
  journal={Extremophiles},
  year={2000},
  volume={4},
  pages={77-82}
}
  • D. Nies
  • Published 2000
  • Chemistry, Medicine
  • Extremophiles
Abstract In contrast to thermophilic or psychrophilic organisms, heavy metal-resistant bacteria do not supply enzymes that are active under harsh conditions, but are themselves tools for the evaluation and remediation of heavy metal-contaminated environments. Ralstonia sp. CH34 is a gram-negative bacterium with a remarkable set of resistance determinants, allowing this bacterium to live in extreme environments that are heavily contaminated with toxic metal ions. These heavy metal ions are… Expand
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  • D. Nies
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  • FEMS microbiology reviews
  • 2003
TLDR
The complement of efflux systems of 63 sequenced prokaryotes was compared with that of the heavy metal resistant bacterium Ralstonia metallidurans and showed that heavy metal resistance is the result of multiple layers of resistance systems with overlapping substrate specificities, but unique functions. Expand
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A first inventory of metal resistance genes and operons across R. metallidurans suggests that metal-resistant Ralstonia, through evolution, are particularly well adapted to the harsh environments typically created by extreme anthropogenic situations or biotopes. Expand
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