Heavy and light roles: myosin in the morphogenesis of the heart

Abstract

Myosin is an essential component of cardiac muscle, from the onset of cardiogenesis through to the adult heart. Although traditionally known for its role in energy transduction and force development, recent studies suggest that both myosin heavy-chain and myosin light-chain proteins are required for a correctly formed heart. Myosins are structural proteins… (More)
DOI: 10.1007/s00018-012-1131-1

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