Heat stress activates ER stress signals which suppress the heat shock response, an effect occurring preferentially in the cortex in rats

Abstract

Although heat stress induces a variety of illnesses, there have been few studies designed to uncover the molecular mechanisms underlining the illnesses. We here demonstrate that heat activates ER stress, which inhibits heat shock responses (HSR) via translational block. In heat-stressed rats, ER stress responses, as represented by eIF2α phosphorylation and… (More)
DOI: 10.1007/s11033-011-1179-2

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@article{Liu2011HeatSA, title={Heat stress activates ER stress signals which suppress the heat shock response, an effect occurring preferentially in the cortex in rats}, author={Yaohua Liu and Hiroaki Sakamoto and M Adachi and Shiguang Zhao and Wataru Ukai and Eri Hashimoto and Masato Hareyama and Tadao Ishida and Kohzoh Imai and Yasuhisa Shinomura}, journal={Molecular Biology Reports}, year={2011}, volume={39}, pages={3987-3993} }