Heat shock proteins and virus replication: hsp70s as mediators of the antiviral effects of prostaglandins

Acute infection of mammalian cells with several types of RNA and DNA viruses often results in induction of heat-shock gene expression. The presence of hsp70 in intact virions, as well as the transient association of HSP with viral proteins and assembly intermediates during virus replication, has also been reported in several experimental models. Moreover, a… CONTINUE READING