Heat shock proteins and other components of cellular machinery for protein synthesis are up-regulated in vascular endothelial cell growth factor-activated human endothelial cells.

@article{Pawlowska2005HeatSP,
  title={Heat shock proteins and other components of cellular machinery for protein synthesis are up-regulated in vascular endothelial cell growth factor-activated human endothelial cells.},
  author={Zofia Pawlowska and Patrycja Barańska and Hanna Jerczyńska and Wiktor Koziolkiewicz and Czeslaw S. Cierniewski},
  journal={Proteomics},
  year={2005},
  volume={5 5},
  pages={1217-27}
}
Proteome analysis of human umbilical endothelial cells was performed to identify proteins that are modified during vascular endothelial cell growth factor (VEGF)-induced transition from the quiescent into the proliferating-migrative phenotype. Subtractive analysis of two-dimensional gel patterns of human endothelial cells, before and after stimulation with VEGF(165), revealed differences in 85 protein spots. All proteins were identified by peptide sequencing and peptide mass fingerprinting… CONTINUE READING

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