Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways.

@article{Parcellier2003HeatSP,
  title={Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways.},
  author={Arnaud Parcellier and Sandeep Gurbuxani and Elise Schmitt and {\'E}ric Solary and Carmen Garrido},
  journal={Biochemical and biophysical research communications},
  year={2003},
  volume={304 3},
  pages={505-12}
}
Stress or heat shock proteins (HSPs) are ubiquitous and highly conserved proteins whose expression is induced in response to a wide variety of physiological and environmental insults. They allow the cells to survive to otherwise lethal conditions. Various mechanisms have been proposed to account for the cytoprotective functions of HSPs. These proteins play an essential role in intracellular "house-keeping" by assisting the correct folding of nascent and stress-accumulated misfolded proteins and… CONTINUE READING

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