Heat shock protein-peptide complexes in cancer immunotherapy.

  title={Heat shock protein-peptide complexes in cancer immunotherapy.},
  author={Pramod K. Srivastava and Heiichiro Udono},
  journal={Current opinion in immunology},
  volume={6 5},
Heat shock proteins (HSPs) are associated with a broad spectrum of peptides derived from the cells from which they are isolated. Vaccination with such HSP-peptide complexes elicits protective immunity against tumors or other cells used as the source of HSPs. These observations suggest that HSP-peptide complexes are suitable as vaccines against cancers and infectious diseases. 
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