Heat-shock protein HSP70 protects neuroblastoma cells SK-N-SH from the neurotoxic effects of hydrogen peroxide and the β-amyloid peptide

Neuronal cell death in Alzheimer’s disease is associated with the development of oxidative stress caused by the reactive oxygen species (ROS), which can be generated as a result of the effect of beta-amyloid peptides. One of the sources of ROS is hydrogen peroxide, inducing the apoptosis and necrosis of neural tissue cells. The mechanism of hydrogen… CONTINUE READING