Heat shock protein 90 inhibitors induce functional inhibition of human natural killer cells in a dose-dependent manner.

Abstract

Heat shock protein 90 (Hsp90) is a ubiquitously expressed ATP-dependent molecular chaperone across all species that helps to the correct the folding of many proteins related to important signaling pathways. Tumor cells expressing Hsp90 have more ATP-binding affinity than normal cells. Many correlative inhibitors have been developed to promising anti-tumor… (More)
DOI: 10.3109/08923973.2015.1119159

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Cite this paper

@article{Huyan2016HeatSP, title={Heat shock protein 90 inhibitors induce functional inhibition of human natural killer cells in a dose-dependent manner.}, author={Ting Huyan and Qi Li and Dan-dan Dong and Hui Yang and Jian Zhang and Qing-sheng Huang and Da-Chuan Yin and Peng Shang}, journal={Immunopharmacology and immunotoxicology}, year={2016}, volume={38 2}, pages={77-86} }