Heat shock protein 72 level decreases during sleep in patients with obstructive sleep apnea syndrome.

@article{Noguchi1997HeatSP,
  title={Heat shock protein 72 level decreases during sleep in patients with obstructive sleep apnea syndrome.},
  author={T. Noguchi and K. Chin and M. Ohi and H. Kita and N. Otsuka and T. Tsuboi and M. Satoh and A. Nakai and K. Kuno and K. Nagata},
  journal={American journal of respiratory and critical care medicine},
  year={1997},
  volume={155 4},
  pages={
          1316-22
        }
}
  • T. Noguchi, K. Chin, +7 authors K. Nagata
  • Published 1997
  • Medicine
  • American journal of respiratory and critical care medicine
    • Patients with obstructive sleep apnea syndrome (OSAS) suffer from stresses related to repetitive apneas during sleep. To examine whether the level of 72 kDa heat shock protein (HSP72) increases during sleep, 11 OSAS patients (apnea-hypopnea index: 63.5 +/- 36.1, mean +/- SD) underwent polysomnography and their peripheral blood mononuclear cells (PBMC) were isolated before, during, and after sleep. HSP72 level was determined by Western blotting and hsp72 mRNA level was quantified by Northern… CONTINUE READING
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