Heat shock protein 70 and HLA-DR molecules tissue expression. Prognostic implications in colorectal cancer.

@article{Lazaris1995HeatSP,
  title={Heat shock protein 70 and HLA-DR molecules tissue expression. Prognostic implications in colorectal cancer.},
  author={Andreas M. Lazaris and George E. Theodoropoulos and Panagiotis S. Davaris and Dimitris Panoussopoulos and Lydia Dr Nakopoulou and Christos N. Kittas and Basil Ch. Golematis},
  journal={Diseases of the colon and rectum},
  year={1995},
  volume={38 7},
  pages={
          739-45
        }
}
PURPOSE The expression of 70,000-Da heat shock protein (HSP 70) and HLA-DR molecules on cancer cells influences immunologic mechanisms that may be of some prognostic significance. The purpose of this study was to examine the relationship among immunohistochemical HSP 70, HLA-DR expression, and clinicopathologic tumor variables, as well as patient survival in a series of 128 colorectal carcinomas. METHOD A three-step immunoperoxidase staining technique was undertaken for detection of both… CONTINUE READING
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