Heat shock-induced HIKESHI protects cell viability via nuclear translocation of heat shock protein 70.

Abstract

Heat shock proteins (HSPs), particularly HSP70, help restore normal cellular function following damage caused by stressors. HSP expression in tumor tissues indicates cancer progression, and while the development of HSP inhibitors is progressing, these substances are not widely used to treat cancer. HIKESHI (C11orf73) does not control the intracellular… (More)
DOI: 10.3892/or.2017.5844

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