Heat potentiation of radiation damage versus radiation potentiation of heat damage.

@article{Hofer1987HeatPO,
  title={Heat potentiation of radiation damage versus radiation potentiation of heat damage.},
  author={Kurt G. Hofer},
  journal={Radiation research},
  year={1987},
  volume={110 3},
  pages={
          450-7
        }
}
The enhanced lethality of mammalian cells after combined treatment with hyperthermia and radiation is usually attributed to heat potentiation of radiation damage. However, it has been suggested that the situation may be reversed and that radiation may act as a modifier for heat damage. To test this hypothesis, BP-8 murine sarcoma cells were subjected to sequential radiation and heat treatments and the kinetics and extent of cell death were evaluated with the [125I]-iododeoxyuridine prelabeling… CONTINUE READING