Heat intolerance: does gene transcription contribute?

  title={Heat intolerance: does gene transcription contribute?},
  author={D. S. Moran and Luba Eli-Berchoer and Yuval Heled and Liran Mendel and Mara Schocina and Michal Horowitz},
  journal={Journal of applied physiology},
  volume={100 4},
During exertion in the heat, heat-intolerant (HI) subjects have a physiological disability in metabolic heat dissipation. The HI state is either permanent or temporary, depending on whether it stems from transient predisposing factors or inherent thermoregulatory dysfunction. In this investigation, we studied protein levels of heat shock protein (HSP) 70 and HSP72, HSP90, bcl-2xL, glutathione S-transferase-p, heat shock factor-1, TATA-binding protein-associated factor, and NF-kappaB transcripts… CONTINUE READING


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