Heat acclimation prolongs the time to central nervous system oxygen toxicity in the rat. Possible involvement of HSP72.

@article{Arieli2003HeatAP,
  title={Heat acclimation prolongs the time to central nervous system oxygen toxicity in the rat. Possible involvement of HSP72.},
  author={Yehuda Arieli and Mirit Eynan and Hanan Gancz and Ran Arieli and Yechezkel Kashi},
  journal={Brain research},
  year={2003},
  volume={962 1-2},
  pages={15-20}
}
Oxygen toxicity of the central nervous system (CNS-OT) can occur during diving with oxygen-enriched gas mixtures, or during hyperbaric medical treatment. CNS-OT is characterised by convulsions and sudden loss of consciousness, which may be fatal in diving. Heat acclimation is known to provide cross-tolerance to various forms of stress in different organs, including the brain. We hypothesised that heat acclimation may delay the onset of CNS-OT in the rat. Male Sprague-Dawley rats were acclimated… CONTINUE READING

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