Heat Shock Protein-27, -60 and -90 expression in gastric cancer: association with clinicopathological variables and patient survival

@inproceedings{Giaginis2009HeatSP,
  title={Heat Shock Protein-27, -60 and -90 expression in gastric cancer: association with clinicopathological variables and patient survival},
  author={Constantinos T. Giaginis and Stella S Daskalopoulou and Stephanie Vgenopoulou and Ioannis K Sfiniadakis and Gregorios P. Kouraklis and Stamatios Theocharis},
  booktitle={BMC gastroenterology},
  year={2009}
}
BACKGROUND Heat shock proteins (HSPs) are ubiquitous, highly conserved proteins across all the species and play essential roles in maintaining protein stability within the cells under normal conditions, while preventing stress-induced cellular damage. HSPs were also overexpressed in various types of cancer, being associated with tumor cell proliferation, differentiation and apoptosis. The aim of the present study was to evaluate the clinical significance of HSP -27, -60, and -90 expression in… CONTINUE READING

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