Heartworms, macrocyclic lactones, and the specter of resistance to prevention in the United States

@inproceedings{Bowman2012HeartwormsML,
  title={Heartworms, macrocyclic lactones, and the specter of resistance to prevention in the United States},
  author={Dwight Douglas Bowman},
  booktitle={Parasites & Vectors},
  year={2012}
}
In order to provide a background to current concerns relative to the possible resistance of heartworms to macrocyclic lactones, this review summarizes various studies in which lack of efficacies (LOEs) have been observed in dogs on macrocyclic lactone preventives relative to the United States of America. Some of these studies have been published in the peer-reviewed literature, others have appeared in various reports to the Center for Veterinary Medicine (CVM) of the Food and Drug… CONTINUE READING
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