Heart tumors specifically induced in young avian embryos by the v-myc oncogene.

@article{Saule1987HeartTS,
  title={Heart tumors specifically induced in young avian embryos by the v-myc oncogene.},
  author={Simon Saule and J P M{\'e}rigaud and A E Al-Moustafa and Françoise Ferr{\'e} and P M Rong and Philippe Amouyel and Brigitte Quatannens and Dominique St{\'e}helin and Françoise Dieterlen-Li{\'e}vre},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1987},
  volume={84 22},
  pages={7982-6}
}
To determine if expression of the v-myc oncogene had any effect during ontogeny, we injected avian myelocytomatosis virus strain MC29 into avian embryos at various stages of development. The injection of MC29 at embryonic day 2 (E2) or 3 (E3) caused, about 10 days later, rhabdomyosarcomas of the heart and, in some cases, skin muscle hypertrophy. When the injection was performed at E4 or E5, the number of heart tumors declined, whereas the number of skin muscle tumors increased significantly… CONTINUE READING

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