Heart transplantation in children with markedly elevated pulmonary vascular resistance: impact of right ventricular failure on outcome.

@article{OforiAmanfo2011HeartTI,
  title={Heart transplantation in children with markedly elevated pulmonary vascular resistance: impact of right ventricular failure on outcome.},
  author={George Ofori-Amanfo and Daphne T. Hsu and Jacqueline Lamour and Seema R Mital and Michael L. O'Byrne and Arthur J. Smerling and Jonathan M. Chen and Ralph S. Mosca and Linda J. Addonizio},
  journal={The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation},
  year={2011},
  volume={30 6},
  pages={659-66}
}
BACKGROUND Pulmonary hypertension causes increased morbidity and mortality in adults after heart transplantation. The effect of markedly elevated pulmonary vascular resistance (PVR) on post-transplant outcomes in children has not been well described. METHODS Outcomes were compared in a retrospective study between 58 children with an elevated PVR index (PVRI) ≥ 6 U/m(2) and 205 children with a PVRI < 6 U/m(2). Patients who did and did not respond to acute vasodilator testing and patients who… CONTINUE READING
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