Heart to heart with trastuzumab: a review on cardiac toxicity

@article{Cosimo2011HeartTH,
  title={Heart to heart with trastuzumab: a review on cardiac toxicity},
  author={Serena Di Cosimo},
  journal={Targeted Oncology},
  year={2011},
  volume={6},
  pages={189-195}
}
Trastuzumab is regarded as the foundation of care for HER2-positive breast cancer as it has revolutionized the treatment of this disease across all settings. Although generally well tolerated, patients may develop symptomatic or asymptomatic cardiotoxicity, forcing a discontinuation of treatment, therefore preventing patients from benefiting from maximal disease control. Evolving research supports that trastuzumab-induced cardiotoxicity may be prevented or at least minimized by a number of… CONTINUE READING