Heart rate as a prognostic risk factor in patients with coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a subgroup analysis of a randomised controlled trial

@article{Fox2008HeartRA,
  title={Heart rate as a prognostic risk factor in patients with coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a subgroup analysis of a randomised controlled trial},
  author={K. Fox and I. Ford and P. Steg and M. Tendera and M. Robertson and R. Ferrari},
  journal={The Lancet},
  year={2008},
  volume={372},
  pages={817-821}
}
BACKGROUND The BEAUTIFUL study assessed the morbidity and mortality benefits of the heart rate-lowering agent ivabradine. The placebo arm of the BEAUTIFUL trial was a large cohort of patients with stable coronary artery disease and left-ventricular dysfunction. We did a subanalysis of this placebo group to test the hypothesis that elevated resting heart rate at baseline is a marker for subsequent cardiovascular death and morbidity. METHODS The association of baseline resting heart rate with… Expand
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