Heart rate and pulse pressure variability are associated with intractable intracranial hypertension after severe traumatic brain injury.

@article{Kahraman2010HeartRA,
  title={Heart rate and pulse pressure variability are associated with intractable intracranial hypertension after severe traumatic brain injury.},
  author={Sibel Kahraman and Richard P. Dutton and Peter Hu and Lynn G. Stansbury and Yongying Xiao and Deborah M. Stein and Thomas M. Scalea},
  journal={Journal of neurosurgical anesthesiology},
  year={2010},
  volume={22 4},
  pages={
          296-302
        }
}
Calculation of integer heart rate variability (HRVi) permits monitoring over extended periods. We asked whether continuous monitoring of HRVi or integer pulse pressure (PP) variability (PPVi) could predict intracranial hypertension, defined as ICP >20 mm Hg, cerebral hypoperfusion, defined as CPP<60 mm Hg, mortality or functional outcome after severe traumatic brain injury. Dense integer data collected during continuous intensive care unit monitoring for periods of 1 to 11 days on 25 patients… CONTINUE READING

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