Heart infarct in NOD-SCID mice: therapeutic vasculogenesis by transplantation of human CD34+ cells and low dose CD34+KDR+ cells.

@article{Botta2004HeartII,
  title={Heart infarct in NOD-SCID mice: therapeutic vasculogenesis by transplantation of human CD34+ cells and low dose CD34+KDR+ cells.},
  author={R. F. Botta and E. Mei Gao and Giorgio Stassi and D{\'e}sir{\'e}e Bonci and Elvira Pelosi and Donna R. Zwas and Mariella Patti and Lucrezia Colonna and Marta Baiocchi and Simona Coppola and Xin Ma and Gianluigi Condorelli and Cesare Peschle},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2004},
  volume={18 12},
  pages={1392-4}
}
Hematopoietic (Hem) and endothelial (End) lineages derive from a common progenitor cell, the hemangioblast: specifically, the human cord blood (CB) CD34+KDR+ cell fraction comprises primitive Hem and End cells, as well as hemangioblasts. In humans, the potential therapeutic role of Hem and End progenitors in ischemic heart disease is subject to intense investigation. Particularly, the contribution of these cells to angiogenesis and cardiomyogenesis in myocardial ischemia is not well established… CONTINUE READING

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