Heart hypertrophy during pregnancy: a better functioning heart?

  title={Heart hypertrophy during pregnancy: a better functioning heart?},
  author={Mansoureh Eghbali and Yibin Wang and Ligia Toro and Enrico Stefani},
  journal={Trends in cardiovascular medicine},
  volume={16 8},
During pregnancy, healthy women develop ventricular hypertrophy and diastolic dysfunction as a result of volume overload as well as increased stretch and force demand. Pregnancy also induces electrocardiogram disturbances such as longer QT-interval dispersion. Surprisingly, it was not until recently that the underlying molecular mechanisms or the role of sex hormones was addressed in this critical female reproductive stage. Recent work with the use of mouse and rat models show that the… CONTINUE READING


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