Heart-focused anxiety as a mediating variable in the treatment of noncardiac chest pain by cognitive-behavioral therapy and paroxetine.

@article{Spinhoven2010HeartfocusedAA,
  title={Heart-focused anxiety as a mediating variable in the treatment of noncardiac chest pain by cognitive-behavioral therapy and paroxetine.},
  author={Philip Spinhoven and A. J. Willem van der Does and Eduard van Dijk and Yanda R. van Rood},
  journal={Journal of psychosomatic research},
  year={2010},
  volume={69 3},
  pages={227-35}
}
OBJECTIVE We compared the efficacy of cognitive behavior therapy (CBT), paroxetine and placebo in the treatment of noncardiac chest pain (NCCP). We also investigated whether pre- to mid-treatment reduction of (heart-focused) anxiety mediated mid- to post-treatment pain reduction. METHODS Sixty-nine adults with NCCP were randomly assigned to 16 weeks of outpatient treatment with CBT, paroxetine or placebo. The comparison between placebo and paroxetine was carried out in a double-blind fashion… CONTINUE READING