Heart failure with preserved ejection fraction is characterized by dynamic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocardial energy deficiency.

@article{Phan2009HeartFW,
  title={Heart failure with preserved ejection fraction is characterized by dynamic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocardial energy deficiency.},
  author={Thanh Trung Phan and Khalid Abozguia and Ganesh Nallur Shivu and Gnanadevan Mahadevan and Ibrar Ahmed and Lynne M. Williams and Girish Dwivedi and Kiran M. Patel and Paul Steendijk and Houman Ashrafian and Anke Henning and Michael Paul Frenneaux},
  journal={Journal of the American College of Cardiology},
  year={2009},
  volume={54 5},
  pages={
          402-9
        }
}
OBJECTIVES We sought to evaluate the role of exercise-related changes in left ventricular (LV) relaxation and of LV contractile function and vasculoventricular coupling (VVC) in the pathophysiology of heart failure with preserved ejection fraction (HFpEF) and to assess myocardial energetic status in these patients. BACKGROUND To date, no studies have investigated exercise-related changes in LV relaxation and VVC as well as in vivo myocardial energetic status in patients with HFpEF. METHODS… CONTINUE READING
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