Heart Rate Recovery Immediately After Treadmill Exercise and Left Ventricular Systolic Dysfunction as Predictors of Mortality: The Case of Stress Echocardiography

  title={Heart Rate Recovery Immediately After Treadmill Exercise and Left Ventricular Systolic Dysfunction as Predictors of Mortality: The Case of Stress Echocardiography},
  author={Junko Watanabe and Maran Thamilarasan and Eugene H. Blackstone and James D. Thomas and Michael S. Lauer},
  journal={Circulation: Journal of the American Heart Association},
Background—An attenuated heart rate recovery after exercise has been shown to be predictive of mortality. In prior studies, recovery heart rates were measured while patients were exercising lightly, that is, during a cool-down period. It is not known whether heart rate recovery predicts mortality when measured in the absence of a cool-down period or after accounting for left ventricular systolic function. Methods and Results—We followed 5438 consecutive patients without a history of heart… 

Figures and Tables from this paper

Abnormal heart rate recovery immediately after cardiopulmonary exercise testing in heart failure patients.

It seems that the attenuated HRR value one minute after peak exercise appears to be a reliable index of the severity of exercise intolerance in heart failure patients and this study supports the value of HRR as a prognostic marker amongheart failure patients referred for cardiopulmonary exercise testing for prediction of prognosis.

Determinants of heart rate recovery in patients with suspected coronary artery disease.

The results suggested that heart rate recovery is associated with clinical factors related to the cardiac autonomic function such as diabetes mellitus and heart rate at rest, but not with other ones such as left ventricular geometry and myocardial ischemia.

Abnormal heart rate recovery immediately after treadmill testing: Correlation with clinical, exercise testing, and myocardial perfusion parameters

Early heart rate recovery after exercise predicts mortality in patients with chronic heart failure.

Sympathetic excitation during exercise as a cause of attenuated heart rate recovery in patients with myocardial infarction.

Enhanced sympathetic excitation at maximum exercise suppresses parasympathetic reactivation and results in attenuation of HRR, a predictor of cardiac death in patients with heart disease.

Heart rate recovery after exercise: a predictor of ventricular fibrillation susceptibility after myocardial infarction.

Data suggest that resistant animals exhibit a more rapid recovery of vagal activity after exercise than those susceptible to VF, and may help identify patients with a high risk for VF following myocardial infarction.

Changes in Heart Rate during and after Exercise Treadmill Test as Prognostic Factor in Cardiovascular Disease

Parameters in exercise treadmill test, such as maximal exercise capacity, HRR, DHR and achievement of 85% MPHR, appear to provide additional information and are important variables associated with the prediction of risk in cardiac events.

Heart Rate Recovery in Coronary Artery Disease and the Changes of Exercise Parameters after Coronary Stenting

The frequency of abnormal heart rate recovery was significantly higher in the coronary artery disease group and the Duke treadmill score was significantly improved and is thought to be a useful follow up parameter after coronary stenting.



Heart-rate recovery immediately after exercise as a predictor of mortality.

A delayed decrease in the heart rate during the first minute after graded exercise, which may be a reflection of decreased vagal activity, is a powerful predictor of overall mortality, independent of workload, the presence or absence of myocardial perfusion defects, and changes inheart rate during exercise.

Vagally mediated heart rate recovery after exercise is accelerated in athletes but blunted in patients with chronic heart failure.

Heart Rate Recovery after Submaximal Exercise Testing as a Predictor of Mortality in a Cardiovascularly Healthy Cohort

The goal was to examine heart rate recovery as a predictor of long-term mortality in a population-based cohort of adults without evidence of cardiovascular disease who underwent submaximal exercise testing.

Modulation of cardiac autonomic activity during and immediately after exercise.

A marked reduction of autonomic modulation of heart rate in patients with heart failure and after cardiac transplant is demonstrated and a progressive withdrawal of vagal activity during exercise with a gradual increase during recovery in normal subjects is supported.

Reduced Heart Rate Variability and Mortalit Risk in an Elderly Cohort: The Framingham Heart Study

The estimation of heart rate variability by ambulatory monitoring offers prognostic information beyond that provided by the evaluation of traditional risk factors.

Use of exercise echocardiography for prognostic evaluation of patients with known or suspected coronary artery disease.

Complementary value of two-dimensional exercise echocardiography to routine treadmill exercise testing.

It is concluded that exercise echocardiography is a valuable addition to routine treadmill testing and may be of special value in patients with an abnormal resting electrocardiogram or a nondiagnostic response to treadmill testing or when a false-negative treadmill test is suspected.