Hearing impairment in genotyped Wolfram syndrome patients.

  title={Hearing impairment in genotyped Wolfram syndrome patients.},
  author={Rutger F. Plantinga and Ronald J. E. Pennings and Patrick L. M. Huygen and Rocco Bruno and Philipp Eller and Timothy G Barrett and Bernard Vialettes and Veronique Paquis-Fluklinger and Fortunato Lombardo and Cor W. R. J. Cremers},
  journal={The Annals of otology, rhinology, and laryngology},
  volume={117 7},
OBJECTIVES Wolfram syndrome is a progressive neurodegenerative syndrome characterized by the features "DIDMOAD" (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness). We sought to study the audiometric data of genotyped Wolfram syndrome patients with sensorineural hearing impairment. METHODS Pure tone threshold data of 23 Wolfram syndrome… CONTINUE READING