Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials.

Abstract

BACKGROUND Researchers and organizations often use evidence from randomized controlled trials (RCTs) to determine the efficacy of a treatment or intervention under ideal conditions. Studies of observational designs are often used to measure the effectiveness of an intervention in 'real world' scenarios. Numerous study designs and modifications of existing… (More)
DOI: 10.1002/14651858.MR000034.pub2

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