Health risk assessment of long-term exposure to non-genotoxic chemicals: application of biological indices.

@article{Lauwerys1995HealthRA,
  title={Health risk assessment of long-term exposure to non-genotoxic chemicals: application of biological indices.},
  author={Robert R. Lauwerys and Alfred Bernard and Harry A. Roels and J. P. Buchet},
  journal={Toxicology letters},
  year={1995},
  volume={77 1-3},
  pages={39-44}
}
For chemical pollutants, health risk assessment of long-term exposure is usually best realized through an epidemiologic approach which attempts to link cumulative levels of exposure to the potential for occurrence of early adverse effects. For some chemicals, however, the frequency of peak exposures may be more relevant for assessing the health risk than the integrated dose. In very few circumstances, biological exposure indices directly reflect the cumulative dose (e.g. PCB in blood). More… CONTINUE READING