Health related quality of life six months following surgical treatment for secondary peritonitis – using the EQ-5D questionnaire

Abstract

BACKGROUND To compare health related quality of life (HR-QoL) in patients surgically treated for secondary peritonitis to that of a healthy population. And to prospectively identify factors associated with poorer (lower) HR-QoL. DESIGN A prospective cohort of secondary peritonitis patients was mailed the EQ-5D and EQ-VAS 6-months following initial laparotomy. SETTING Multicenter study in two academic and seven regional teaching hospitals. PATIENTS 130 of the 155 eligible patients (84%) responded to the HR-QoL questionnaires. RESULTS HR-QoL was significantly worse on all dimensions in peritonitis patients than in a healthy reference population. Peritonitis characteristics at initial presentation were not associated with HR-QoL at six months. A more complicated course of the disease leading to longer hospitalization times and patients with an enterostomy had a negative impact on the mobility (p = 0.02), self-care (p < 0.001) and daily activities: (p = 0.01). In a multivariate analysis for the EQ-VAS every doubling of hospital stay decreases the EQ-VAS by 3.8 points (p = 0.015). Morbidity during the six-month follow-up was not found to be predictive for the EQ-5D or EQ-VAS. CONCLUSION Six months following initial surgery, patients with secondary peritonitis report more problems in HR-QoL than a healthy reference population. Unfavorable disease characteristics at initial presentation were not predictive for poorer HR-QoL, but a more complicated course of the disease was most predictive of HR-QoL at 6 months.

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@article{Boer2007HealthRQ, title={Health related quality of life six months following surgical treatment for secondary peritonitis – using the EQ-5D questionnaire}, author={Kimberly Rachel Boer and Oddeke van Ruler and Johannes B. Reitsma and Cecilia W. Mahler and Brent C. Opmeer and E. Ascelijn Reuland and H. G. Gooszen and Peter W de Graaf and Eric J Hesselink and Michael Gerhards and E. Philip Steller and Mirjam A. G. Sprangers and Marja A. Boermeester and Corianne A. J. M. de Borgie}, journal={Health and Quality of Life Outcomes}, year={2007}, volume={5}, pages={35 - 35} }