Health-related quality of life in patients with autosomal dominant polycystic kidney disease and CKD stages 1-4: a cross-sectional study.

@article{Miskulin2014HealthrelatedQO,
  title={Health-related quality of life in patients with autosomal dominant polycystic kidney disease and CKD stages 1-4: a cross-sectional study.},
  author={Dana C. Miskulin and Kaleab Z Abebe and Arlene B. Chapman and Ronald D. Perrone and Theodore I. Steinman and Vicente E. Torres and K. T. Bae and William E. Braun and Franz T. Winklhofer and Marie Hogan and Fred Rahbari-Oskoui and Charity G Moore and Michael Francis Flessner and Robert W. Schrier},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2014},
  volume={63 2},
  pages={
          214-26
        }
}
BACKGROUND In people with early autosomal dominant polycystic kidney disease (ADPKD), average total kidney volume (TKV) is 3 times normal and increases by an average of 5% per year despite a seemingly normal glomerular filtration rate (GFR). We hypothesized that increased TKV would be a source of morbidity and diminished quality of life that would be worse in patients with more advanced disease. STUDY DESIGN Cross-sectional. SETTING & PARTICIPANTS 1,043 patients with ADPKD, hypertension… CONTINUE READING

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