Health-related quality of life assessment and reported outcomes in leukaemia randomised controlled trials - a systematic review to evaluate the added value in supporting clinical decision making.

@article{Efficace2008HealthrelatedQO,
  title={Health-related quality of life assessment and reported outcomes in leukaemia randomised controlled trials - a systematic review to evaluate the added value in supporting clinical decision making.},
  author={Fabio Efficace and Georg Kemmler and Marco Vignetti and Franco Mandelli and Stefano Molica and Bernhard Holzner},
  journal={European journal of cancer},
  year={2008},
  volume={44 11},
  pages={1497-506}
}
Health-related quality of life (HRQOL) is increasingly reported as an important outcome in cancer clinical trials. However, very little evidence exists on the impact of such evaluation in randomised controlled trials (RCTs) of leukaemia patients. A systematic search of the literature from 1980 to 2007 was undertaken and studies were identified and evaluated independently, according to a pre-defined coding scheme, by three reviewers. Both HRQOL outcomes and traditional clinical reported outcomes… CONTINUE READING
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