Health of lake whitefish (Coregonus clupeaformis) with elevated tissue levels of environmental contaminants.

@article{Mikaelian2002HealthOL,
  title={Health of lake whitefish (Coregonus clupeaformis) with elevated tissue levels of environmental contaminants.},
  author={Igor Mikaelian and Yves de Lafontaine and John C. Harshbarger and Lucy Lee and Daniel Martineau},
  journal={Environmental toxicology and chemistry},
  year={2002},
  volume={21 3},
  pages={532-41}
}
Lake whitefish (Coregonus clupeaformis) were collected in 1996 from the St. Lawrence River, Quebec, Canada. Histologic examination was performed on major organs of 497 specimens and on the liver of 48 additional individuals. Preneoplastic and neoplastic hepatic changes consisted of vacuolated cell (n = 65), clear cell (n = 17), and acidophilic (n = 16) foci of altered hepatocyte, hepatocellular carcinoma (n = 12), cholangioma (n = 5), and cholangiocarcinoma (n = 28). Six fish were intersexes (1… CONTINUE READING

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