• Corpus ID: 28239079

Health effects of garlic.

@article{Tattelman2005HealthEO,
  title={Health effects of garlic.},
  author={Ellen P. Tattelman},
  journal={American family physician},
  year={2005},
  volume={72 1},
  pages={
          103-6
        }
}
  • E. Tattelman
  • Published 1 July 2005
  • Medicine
  • American family physician
Garlic has long been used medicinally, most recently for its cardiovascular, antineoplastic, and antimicrobial properties. Sulfur compounds, including allicin, appear to be the active components in the root bulb of the garlic plant. Studies show significant but modest lipid-lowering effects and antiplatelet activity. Significant blood pressure reduction is not consistently noted. There is some evidence for antineoplastic activity and insufficient evidence for clinical antimicrobial activity… 

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References

SHOWING 1-10 OF 28 REFERENCES

Comparison of the efficacy and tolerance of a garlic preparation vs. bezafibrate.

There was no correlation between the perception of garlic odour and the influence on the cholesterol level, and the garlic preparation was investigated in a randomized double-blind study vs. bezafibrate.

The effect of garlic supplements on the pharmacokinetics of saquinavir.

Patients should use caution when combining garlic supplements with saquinavir when it is used as a sole protease inhibitor, and the AUC, trough, and Cmax values returned to 60%-70% of their values at baseline.

Effect of a garlic oil preparation on serum lipoproteins and cholesterol metabolism: a randomized controlled trial.

The commercial garlic oil preparation investigated had no influence on serum lipoproteins, cholesterol absorption, or cholesterol synthesis, and garlic therapy for treatment of hypercholesterolemia cannot be recommended on the basis of this study.

Does garlic alter the lipid pattern in normal volunteers?

[Pleiotropic effects of garlic].

These pleiotropic effects of garlic result in a reduction of relative cardiovascular risk for infarction and stroke by more than 50%.

Garlic extract therapy in children with hypercholesterolemia.

Garlic extract therapy has no significant effect on cardiovascular risk factors in pediatric patients with familial hyperlipidemia and is efficacious and safe in children with hypercholesterolemia.

Garlic as a Lipid Lowering Agent—A Meta-Analysis

  • C. SilagyA. Neil
  • Medicine
    Journal of the Royal College of Physicians of London
  • 1994
Using garlic therapy, either as dried garlic preparations or as fresh, high allicin yielding garlic, appears significantly to reduce total serum cholesterol over a 1–3 months period, however, more rigorously designed and analysed trials are needed.

Garlic and cancer: a critical review of the epidemiologic literature.

Evidence from available studies suggests a preventive effect of garlic consumption in stomach and colorectal cancers, and the need for more definitive research and improved nutritional epidemiologic analyses of dietary data is indicated.

Effect of Garlic on Total Serum Cholesterol

A meta-analysis of all randomized, placebo-controlled trials that tested the effectiveness of oral garlic preparations on study groups in which more than 75% of their participants had initial cholesterol levels exceeding 5.17 mmol/L (200 mg/dL) was conducted to produce an overall estimate of treatment effect and to examine the variability ofreatment effect across the combined studies.