Health benefits of wine and alcohol from neuroprotection to heart health.

@article{Vasanthi2012HealthBO,
  title={Health benefits of wine and alcohol from neuroprotection to heart health.},
  author={Hannah R. Vasanthi and Royapuram P Parameswari and J Deleiris and Dipak Kumar Das},
  journal={Frontiers in bioscience},
  year={2012},
  volume={4},
  pages={
          1505-12
        }
}
Controversy is common during efforts to define the role of nutrition in health, but few modern reflections of such controversy are as vivid as the debate over wine. There exists no query that chronic alcohol abuse, a leading worldwide problem, causes neuronal dysfunction and brain damage. However, various epidemiologic studies in recent years have indicated that in comparisons with abstainers or never drinkers, light/moderate alcohol/wine consumers have lower risks of age-dependent cognitive… 

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References

SHOWING 1-10 OF 88 REFERENCES
Alcohol in moderation, cardioprotection, and neuroprotection: epidemiological considerations and mechanistic studies.
TLDR
Moderate alcohol exposure appears to trigger analogous mild stress-associated, anti-inflammatory mechanisms in the heart, vasculature, and brain that tend to promote cellular survival pathways, which could underlie cardioprotection.
The red wine hypothesis: from concepts to protective signalling molecules.
TLDR
Evidence for and against the 'red wine hypothesis', whereby red wine is more likely to confer cardiovascular benefits than white wine are reviewed, and Mechanistic feasibility strengthens the case for prospective therapeutic trials of alcohol vs. red wine vs. resveratrol.
Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide‐related toxicity in cultured hippocampal neurons
Animal and epidemiological studies suggest that polyphenol constituents of red wine possess antioxidant activities that favour protection against cardiovascular disease – the so‐called. ‘French
Resveratrol and red wine, healthy heart and longevity
TLDR
It appears that resveratrol can induce the expression of several longevity genes and prevent aging-related decline in cardiovascular function including cholesterol level and inflammatory response, but it is unable to affect actual survival or life span of mice.
Alcohol intake in relation to brain magnetic resonance imaging findings in older persons without dementia.
TLDR
People whose alcohol consumption was light to moderate had less severe white matter lesions and brain infarcts on MRI than did abstainers or heavy drinkers and, in APOE epsilon4 carriers, hippocampal and amygdalar atrophy on MRI.
Induction of the expression of cardioprotective proteins after mild-to-moderate consumption of alcohol.
  • Motoaki Sato, C. Fraga, D. Das
  • Medicine, Biology
    Pathophysiology : the official journal of the International Society for Pathophysiology
  • 2004
Resveratrol Protects Dopamine Neurons Against Lipopolysaccharide-Induced Neurotoxicity through Its Anti-Inflammatory Actions
TLDR
It is suggested that resveratrol exerts neuroprotection against LPS-induced dopaminergic neurodegeneration, and NADPH oxidase may be a major player in resver atrol-mediated neuroprotection.
Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms
TLDR
Results of the present study indicate that resveratrol significantly reversed 3-nitropropionic acid-induced motor and cognitive impairment, and that the beneficial effects of resver atrol might be attributed to its antioxidant activity.
Red-wine Polyphenols and Inhibition of Platelet Aggregation: Possible Mechanisms, and Potential Use in Health Promotion and Disease Prevention
TLDR
The extract of red-wine grape fermentation contains standardized amounts of the whole spectrum of polyphenolic compounds found in red wine and may provide a valuable reference substance in clinical investigations of the physiological actions of plant polyphenols.
...
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2
3
4
5
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