Health Risks Associated with Inhaled Nasal Toxicants

@article{Feron2001HealthRA,
  title={Health Risks Associated with Inhaled Nasal Toxicants},
  author={Victor J. Feron and Josje H. E. Arts and C Frieke Kuper and Pieter J. Slootweg and Ruud A. Woutersen},
  journal={Critical Reviews in Toxicology},
  year={2001},
  volume={31},
  pages={313 - 347}
}
Health risks of inhaled nasal toxicants were reviewed with emphasis on chemically induced nasal lesions in humans, sensory irritation, olfactory and trigeminal nerve toxicity, nasal immunopathology and carcino-genesis, nasal responses to chemical mixtures, in vitro models, and nasal dosimetry- and metabolism-based extrapolation of nasal data in animals to humans. Conspicuous findings in humans are the effects of outdoor air pollution on the nasal mucosa, and tobacco smoking as a risk factor for… 

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