Healing the Syk through kinase inhibitors.

@article{Rivera2010HealingTS,
  title={Healing the Syk through kinase inhibitors.},
  author={Juan Rivera and Robert A. Colbert},
  journal={The New England journal of medicine},
  year={2010},
  volume={363 14},
  pages={1362-4}
}
Rheumatoid arthritis is a chronic, systemic inflammatory disease that affects close to 1% of the population. It is manifested principally as an attack on peripheral joints and may lead to marked destruction and deformity of joints, with considerable disability. Rheumatoid arthritis is characterized by the production of autoantibodies, synovial inflammation with formation of pannus tissue, and erosion of the underlying cartilage and bone. Despite considerable efforts and significant advances… CONTINUE READING

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