Healing and relapse of reflux esophagitis during treatment with ranitidine.

@article{Koelz1986HealingAR,
  title={Healing and relapse of reflux esophagitis during treatment with ranitidine.},
  author={H R Koelz and R Birchler and A Bretholz and Bernhard Bron and Y Capitaine and Geoffrey Delmore and Holger Fehr and Ivano Fumagalli and J A Gehrig and J. J. Gonvers},
  journal={Gastroenterology},
  year={1986},
  volume={91 5},
  pages={1198-205}
}
In 108 patients the healing and relapse of reflux esophagitis, defined endoscopically by the presence of epithelial defects (erosions and ulcerations) of the esophageal mucosa, were studied. In the first study, with open treatment of ranitidine, the healing rate after 6 wk was 50%. The most important factor that negatively influenced healing was the extent of esophageal erosions. Patients with isolated erosions had a 6-wk healing rate of 78%; the healing rate was 38% in patients with… CONTINUE READING
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