Heads-up: new roles for the fragile X mental retardation protein in neural stem and progenitor cells.

@article{Callan2011HeadsupNR,
  title={Heads-up: new roles for the fragile X mental retardation protein in neural stem and progenitor cells.},
  author={Matthew A Callan and Daniela C. Zarnescu},
  journal={Genesis},
  year={2011},
  volume={49 6},
  pages={424-40}
}
Fragile X syndrome (FXS) is the most common form of inherited mental retardation and is caused by the loss of function for Fragile X Mental Retardation Protein (FMRP), a selective RNA-binding protein with a demonstrated role in the localized translation of target mRNAs at synapses. Several recent studies provide compelling evidence for a new role of FMRP in the development of the nervous system, during neurogenesis. Using a multi-faceted approach and a variety of model systems ranging from… CONTINUE READING
24 Citations
80 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 80 references

Similar Papers

Loading similar papers…