Heads or tails? Amphioxus and the evolution of anterior-posterior patterning in deuterostomes.

@article{Holland2002HeadsOT,
  title={Heads or tails? Amphioxus and the evolution of anterior-posterior patterning in deuterostomes.},
  author={Linda Z Holland},
  journal={Developmental biology},
  year={2002},
  volume={241 2},
  pages={209-28}
}
In Xenopus, the canonical Wnt-signaling pathway acting through beta-catenin functions both in establishing the dorso-ventral axis and in patterning the anterior-posterior axis. This pathway also acts in patterning the animal-vegetal axis in sea urchins. However, because sea urchin development is typically indirect, and adult sea urchins have pentamerous symmetry and lack a longitudinal nerve cord, it has not been clear how the roles of the canonical Wnt-signaling pathway in axial patterning in… CONTINUE READING

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