Heading in a new direction: implications of the revised fate map for understanding Xenopus laevis development.

@article{Lane2006HeadingIA,
  title={Heading in a new direction: implications of the revised fate map for understanding Xenopus laevis development.},
  author={Mary Constance Lane and Michael D. Sheets},
  journal={Developmental biology},
  year={2006},
  volume={296 1},
  pages={12-28}
}
Amphibian embryos have served as a model system for vertebrate axial patterning for more than a century. Recent changes to the Xenopus laevis fate map revised the assignment of the embryonic dorsal/ventral (back-to-belly) axis in pre-gastrula embryos and allowed the assignment of the rostral/caudal (head-to-tail) axis for the first time. Revising the embryonic axes after many years of experimentation changes our view of axial patterning in amphibians. In this review, we discuss the revised maps… CONTINUE READING

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