Headache in mild-to-moderate hypertension and its reduction by irbesartan therapy.

  title={Headache in mild-to-moderate hypertension and its reduction by irbesartan therapy.},
  author={Lennart Hansson and Daniel H. Smith and R Reeves and Pablo Lapuerta},
  journal={Archives of internal medicine},
  volume={160 11},
BACKGROUND Although it is generally acknowledged to be a problem in severe hypertension, headache has not been consistently associated with mild-to-moderate hypertension. PATIENTS AND METHODS In 7 randomized, double-blind, placebo-controlled trials, which included 2,673 patients with mild-to-moderate hypertension (defined as seated diastolic blood pressure of 95-110 mm Hg), patients were randomized to receive once-daily treatment with irbesartan, an angiotensin II receptor blocker (n= 1,987… CONTINUE READING
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