Cerebral venous sinus thrombosis in Behçet’s disease: a retrospective case-control study
A 24-year-old Russian man with a history of recurrent aphthous oral ulcers and a recent episode of genital ulcers presented with severe head and neck pain. Two days after the onset of his symptoms, the patient developed a fever (39-C) and sore throat and was treated for presumed pharyngitis. Four days before presentation, the patient noticed painful genital ulcers (Fig. A) and a rash on his forearm (Fig. B) consistent with folliculitis. The diagnosis of Adamantiades-Beh0et disease was made. A lumbar puncture was performed and was remarkable for an opening pressure of 540 mm Hg with normal cell count. Magnetic resonance venogram (Fig. C; arrowhead depicts lack of flow in transverse sinus) confirmed the diagnosis. The patient was treated with corticosteroids, colchicine, and azathioprine, and his symptoms resolved within weeks.