Head-to-head dimers in the zwitterion of 1-hydroxy-3-(pyrrolidin-1-yl)propylidene-1,1-bisphosphonic acid (EB 1053).


The title compound, 1-hydroxy-1-phosphono-3-(1-pyrrolidinio)propylidene-1-phosphonate, C(7)H(17)NO(7)P(2), is a member of the bisphosphonate class of drugs. As a zwitterion, it possesses a negative charge on one of the PO(3) groups and a positive charge on the pyrrolidine N atom. A zwitterion makes a contact with a neighbouring ion through the hydroxyl O… (More)


  • Presentations referencing similar topics