Head group modulated pH-responsive hydrogel of amino acid-based amphiphiles: entrapment and release of cytochrome c and vitamin B12.

The present study describes the rational design and synthesis of amino acid-based amphiphilic hydrogelators, which were systemically fine-tuned at the head group to develop pH-responsive hydrogels. To understand the basic structural requirements of a low molecular weight amphiphilic hydrogelator, 10 analogous amphiphiles based on L-phenylalanine and L… CONTINUE READING